November 14, 2023
Stoney's British Pub
7:30pm
Stoney's British Pub
3007 Concord Pike
Wilmington, DE
7:30pm
![Struan F.A. Grant / Snooze or Lose: The Impact of Genetics on Sleep Health](https://www.lrsm.upenn.edu/wp-content/uploads/2023/10/SFA-Grant_art-web.png)
Perelman School of Medicine, University of Pennsylvania
“Snooze or Lose: The Impact of Genetics on Sleep Health”
Genome wide surveys in humans have identified genetic signals robustly associated with insomnia and other sleep-related traits, yet little is known about the functional roles of the underlying causal variants in regulating sleep duration or quality. Using a 3D Genomics approach, we identified a number of genes that regulate sleep. Our results provide the first physical variant-to-gene mapping of human sleep genes followed by model organism-based prioritization, revealing novel and conserved processes in sleep regulation.